4794 resultaten
We want to study the effect of feedback to the clinician concerning the motivation of the patient to see if this feedback leads to a better motivation, compliance and treatment result because the clinician is more aware of the motivation (or the…
Since cigarette smoke has effects on the airway epithelium, but also causes endothelial damage and loss of the microvasculature in multiple organs, it seems reasonable to assume that microvascular changes are more present in patients with COPD…
We expect that clinical judgement of medical personnel is better in predicting the development of critical illness compared to the Modified Early Warning Score
Muscular counterpulsation (MCP) is a new treatment option which seems to improve hemodynamics but might also have positive effects on muscular and vascular function. Additionally, it is non-invasive and does not seem to have relevant side effects.…
We expect that patient who receive care according to the protocol about 24/7 availability of specialized palliative care in the home situation, during the year of the study will die more often at home than patients in the years before start of the…
Monitoring quality and yield and giving feedback on performance will increase the quality and yield.
Obinutuzumab can provide clinical benefit in patients with rituximab-refractory follicular lymphoma
Part 1: effect of depth of anesthesia on motor evoked potentials in spinal surgery Primary Objective: To determine the effect of depth of anesthesia, quantified by pEEG, on the characteristics of TES-MEP measurements in spinal surgery. Hypothesis:…
A novel approach/algorithm for individualised risk assessment of COPD exacerbations, which integrates both microbiological data and clinical information, improves the accuracy of exacerbation prediction in COPD patients over methods based on…
An intensive rectal wash-out program for constipated girls with NNBSD is as effective in curing recurrent urinary tract infections as cognitive bladder training in standard outpatient treatment.
1. Alcohol marketing influences youth drinking 2. The following factors moderate of mediate the relationship between marketing & drinking: a. Personal relevance of advertisements, b. Sociability, parental guidance in understanding TV and…
Oral pazopanib once daily is safe and effective in advanced endometrial cancer for which no other therapies are available.
An upfront RBCT aiming at low-normal Hb levels will ameliorate anemia-caused tumor hypoxia-related resistance to chemotherapy before the start of chemotherapy and may decrease secondary anemia-induced endogenous release of cytokines like VEGF,…
Previous randomised trials have shown the efficacy of etanercept in RA patients. In this study we will evaluate the respons of etanercept in anti-TNF naive patients compared to patients who have failed other anti-TNF. We will look for clinical…
Donor-specific antibodies form a significant barrier in transplantation of highly pre-sensitized dialysis patients. Increased waiting time is associated with increased morbidity and mortality among these patients. Thus, there is a need to further…
Home DC-ECV in general population patients with an episode of symptomatic recurrent persistent AF, carried out by ECPs, is feasible, safe and is associated with reduced costs.
Our first hypothesis is that in the two exisiting case management models, the persons with dementia will have less behaviour and mood problems than persons receiving usual care and informal caregivers experience better mental health compared to…
The hypothesis is that low dose GC therapy exerts its anti-inflammatory effect by virtue of a first-pass effect through the liver. It is difficult to directly address the hypothesis, but there is an indirect way of doing so: if indeed low dose GCs…
The EEG profile in responders to methylphenidate will be differ from the EEG profile in non-responders to methylphenidate (i.e. higher total power, increased theta/beta ratio and theta/alpha ratio).
There is no difference between CT- and MRI-based Patient specific matched instruments for total knee arthroplasty