443 resultaten
The aim of this study is to investigate the effect of a short-term experiential Schema Therapy (ST) protocol in individual adult outpatients with cluster C Personality Disorders (PD) on overall wellbeing. Secondary outcomes are attainment of…
Addition of Partner for Change Outcome Management System (PCOMS) to individual treatment will result in a significant decrease of drop-out compared to individual treatment without PCOMS in a forensic outpatient clinic in the Netherlands. A sub-…
The development of a computer aided detection (CAD) system might be able to assist endoscopists in the recognition and subsequent characterization of early Barrett's neoplasia, thereby improving efficacy of BE surveillance.
Morbidity in the post-operative phase of pulmonary surgery is characterised by impairment due to pain, dyspnoea and loss of exercise tolerance. We demonstrated previously that rehabilitation after thoracotomy is limited due to pain. Since minimal…
The goal of the study is to assess the safety culture conversations and see whether they have an impact on the safety attitude on a certain ward or outpatient clinic.
The primary hypothesis is that MRDTI/MRBTI will demonstrate acceptable sensitivity and specificity for the diagnosis of CVT in patients with suspected CVT and an indication for MR-venography, i.e. being a non-diagnostic CVT or contraindication for…
Maternal and neonatal vitamin D level play a role on dental development in childhood
Cardiovascular disease (CVD) is among the most frequent chronic diseases in the Netherlands. So, prevention is of high importance and primary care could play an important role. The cornerstone of CVD prevention is lifestyle change. However,…
To compare patient reported health-related quality of life outcomes (PROs) between BRCA 1 or 2 gene mutation carries who choose breast surveillance or bilateral prophylactic mastectomy with immediate reconstruction.
Approximately 15 to 30% of thyroid nodules evaluated by means of fine-needle aspirate biopsy (FNAB) are not clearly benign or malignant. Patients with cytological indeterminate nodules (Bethesda III/IV) are often referred for diagnostic surgery,…
Enhanced endoscopic imaging, including high-definition white light endoscopy and virtual chromoendoscopy, alongside targeted biopsies provides an accurate and reproducible assessment of chronic atrophic gastritis disease extent and staging, when…
Patients that are treated with lorlatinib will have an impairment in speech, mood and several cognitive domains. With extensive testing, more impairments will be found than with CTCAE criteria alone.
The prevelance of FGID in patients with uncomplicated gallstones is higher compared to the general population
1) an early asthma diagnosis with the breath test will improve disease control, quality of life of children and parents, optimise treatment and thereby improve the prognosis of wheezing children. The use of the breath test will considerably reduce…
Several studies have shown in health subjects that when restricted carbohydrates are ingested, the decrease in portal vein insulin concentration can lead to a reduction in IGF-I synthesis by the liver. However, in pathophysiological states,…
Implementation of chemoprophylaxis can contribute to reducing the transmission by reducing the risk of developing the disease and by the early identification of new patients.The aim of the study is to contribute to interrupting the transmission of M…
To set up a bank of prospectively collected blood samples for pharmacokinetic analyses of monoclonal antibodies and immunophenotyping
Current evidence, mainly from research with breast cancer patients, shows that exercise interventions offered during chemotherapy treatment have positive effect on physical functioning, fatigue and HRQoL. Head and Neck cancer (HNC) patients may also…
Endoscopic placement of fiducial markers in patients with gastric cancer is feasible and beneficial for patient position verification.