324 resultaten
We hypothesize that it is possible to culture circulating tumor cells obtained by leukapheresis into organoids.
- surgical treatment for CMC OA is effective in terms of pain, function and satisfaction - There is a relatively large group of patients with significant residual pain and functional impairment or deterioration of their complaints - Baseline factors…
The Victoria modules are thought to have a positive effect on acknowlegdement for adversities and risk awareness. This can be used to take acceptable risks in rehabilitation process. This will then lead to more societal participation and less…
Since cigarette smoke has effects on the airway epithelium, but also causes endothelial damage and loss of the microvasculature in multiple organs, it seems reasonable to assume that microvascular changes are more present in patients with COPD…
Pruritus or itch is the most common skin symptom in elderly patients and is estimated to affect more than 30% of nursing home patients. Clinical and experimental evidence suggests pruritus in elderly patients may be linked to pemphigoid. Pemphigoid…
Primary Objective: To evaluate whether the replacement of chest X-ray by ultra-low-dose chest CT (ULD chest CT) in the diagnostic work-up of patients suspected of non-traumatic pulmonary disease at the Emergency Department leads to more accurate…
The null-hypothesis states that there is no difference between the intervention group and waiting-list control group on subjective well-being at the three follow-up time-points. The alternative hypothesis states that there is a difference within and…
WE think we can find specific information about psychiatric disorder in the csf of psychiatric patients
Prolonged exposure to supraphysiological levels of GH and/or IGF-1 induces activation of innate immune responses, which might contribute to the long-term CV morbidity in acromegaly patients.
Nonclinical pharmacodynamic studies indicate that InO can be an effective therapeutic agent against B-lymphoid malignancies and support its clinical evaluation as a targeted therapeutic option for B-cell NHL and ALL. Inotuzumab ozogamicin (InO) is a…
We hypothesize a priori that the Dutch NAT: PD-HF will be a feasible and acceptable tool to identify palliative care needs in patients with CHF and will initiate appropriate management.
We expect to demonstrate that ctDNA can be reliably detected in patients with perihilar cholangiocarcinoma.
Investigate if Chronic Fatigue Syndrome patients show signs of neuroinflammation, compared to Q-fever Fatigue Syndrome (QFS) patients and healthy neighbourhood controls.
1. High school Freshman develop less positive attitudes towards substance use after participation in Fresh Start than high school freshman in the waitlist control condition. 2. Fresh Start is more effective when it is implemented at the beginning of…
Cord Derived Dendritic Cell Vaccination directed against WT1 will prevent patients from relapse
DLB patients with concomitant Alzheimer-type pathology (identified by CSF analysis) will have a more severe disease course (with a faster cognitive decline, more prominent structural and functional changes in the brain)
We hypothesise that third molar removal is a safe treatment to perform in healthy patients, but that the experience of a hemmorrhagic complication varies greatly between the patients and surgeons.