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By combining Yttrium-90 radioembolization and Radiofrequency Ablation for treatment of patients with colorectal liver metastases, we might be able to target the remnant tumour cells in the rim of the ablation zone and improve the disease free…
The objective of this pilot study is to evaluate the feasibility of and the satisfaction with a newly developed online self-management program for spousal caregivers of patients with (very) early-stage dementia including prodromal dementia (MCI due…
We hypothesize that high interval physical exercise changes the contribution of adipose tissue and peripheral muscle to human NAFLD and aberrant glucose metabolism via gutmicrobiota mediated plasma metabolites.
to improve the medical care on long term follow up
To evaluate the incidence, risk factors and perinatal morbidity and mortality due to CA after TTTS treated with fetoscopic laser surgery
Gut dysbiosis drives disease processes driving morbidity and mortality in acute pancreatitis, such as infected pancreatic necrosis, and (persistent) multiple organ failure. A decrease in commensal members of the bacterial microbiome allows for…
Which of 2 feeding strategies for children during chemotherapy induced mucositis is optimal for the patient: an elementary diet, containing only simple macronutrients administered via continuous enteral drip; or total parenteral nutrition.
The aim of this study is to analyse breathing patterns during high performance exercise in elite athletes at different modes of exercise while wearing a hexoskin using an incremental exercise test as well as a power profile test.
The aim of the study is to compare two physiotherapeutic rehabiliation strategies (supervised versus less supervised) in patients after hip arthroscopy for FAI and/or labral pathology. The hypothesis is that both groups will equally recover in the…
Focusing on disease-modifying rather than etiologic mechanisms may accelerate the development of novel therapies and complement current research initiatives on causative mechanisms and curative therapies.
Education on guidelines, combined with quality targets within the accreditation procedure improves quality of antibiotic prescribing
Office endometrial sampling is not suitable to diagnose EIN due to the small amount of tissue obtained.
Different prevention strategies are used internationally to prevent Early-onset Group B haemolytic streptococcus infection (EOGBS). However, none of the preventive EOGBS strategies in place at present result in the complete prevention of EOGBS,…
The national quality improvement program palliative care will improve quality of palliative care on a national level and the separate trajectories implementing ‘good practices’ will improve quality of palliative care on the regional and…
We expect that patient who receive care according to the protocol about 24/7 availability of specialized palliative care in the home situation, during the year of the study will die more often at home than patients in the years before start of the…
Part 1: effect of depth of anesthesia on motor evoked potentials in spinal surgery Primary Objective: To determine the effect of depth of anesthesia, quantified by pEEG, on the characteristics of TES-MEP measurements in spinal surgery. Hypothesis:…
Home DC-ECV in general population patients with an episode of symptomatic recurrent persistent AF, carried out by ECPs, is feasible, safe and is associated with reduced costs.
The hypothesis is that low dose GC therapy exerts its anti-inflammatory effect by virtue of a first-pass effect through the liver. It is difficult to directly address the hypothesis, but there is an indirect way of doing so: if indeed low dose GCs…
There is no difference between CT- and MRI-based Patient specific matched instruments for total knee arthroplasty
(1) patient self-monitoring is not inferior to standard of care in terms of DAS 28 score; (2) patient self-monitoring in RA patients will reduce outpatient clinic visits, and will consequently decrease healthcare costs.