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We hypothesize that it is possible to culture circulating tumor cells obtained by leukapheresis into organoids.
By combining Yttrium-90 radioembolization and Radiofrequency Ablation for treatment of patients with colorectal liver metastases, we might be able to target the remnant tumour cells in the rim of the ablation zone and improve the disease free…
The objective of this pilot study is to evaluate the feasibility of and the satisfaction with a newly developed online self-management program for spousal caregivers of patients with (very) early-stage dementia including prodromal dementia (MCI due…
- surgical treatment for CMC OA is effective in terms of pain, function and satisfaction - There is a relatively large group of patients with significant residual pain and functional impairment or deterioration of their complaints - Baseline factors…
To evaluate the incidence, risk factors and perinatal morbidity and mortality due to CA after TTTS treated with fetoscopic laser surgery
No difference in range of motion at 12 months follow-up
Prevalence of PNH in selection of patients with DVT. Patients younger than 30 years of age. patients with DVT on unusual places.
Which of 2 feeding strategies for children during chemotherapy induced mucositis is optimal for the patient: an elementary diet, containing only simple macronutrients administered via continuous enteral drip; or total parenteral nutrition.
Short term dietary restriction will lead to lower concentrations of SN-38 in healthy liver tissue (without reducing the intratumoral concentration) and to less toxicity of irinotecan
The aim of the study is to compare two physiotherapeutic rehabiliation strategies (supervised versus less supervised) in patients after hip arthroscopy for FAI and/or labral pathology. The hypothesis is that both groups will equally recover in the…
1. It is common to stratify a dataset on gender and age when identifying frequent attenders within general practice. However, this could lead to an oversampling of patients with chronic diseases, e.g., cardio-vascular disease or diabetes. We…
Wheelchair mobility skills training and wheelchair fitness training will both increase the level of physical activity in wheelchair using children and adolescents. Wheelchair fitness training prior to wheelchair mobility skills training will show a…
Focusing on disease-modifying rather than etiologic mechanisms may accelerate the development of novel therapies and complement current research initiatives on causative mechanisms and curative therapies.
Education on guidelines, combined with quality targets within the accreditation procedure improves quality of antibiotic prescribing
Different prevention strategies are used internationally to prevent Early-onset Group B haemolytic streptococcus infection (EOGBS). However, none of the preventive EOGBS strategies in place at present result in the complete prevention of EOGBS,…
The Victoria modules are thought to have a positive effect on acknowlegdement for adversities and risk awareness. This can be used to take acceptable risks in rehabilitation process. This will then lead to more societal participation and less…
The national quality improvement program palliative care will improve quality of palliative care on a national level and the separate trajectories implementing ‘good practices’ will improve quality of palliative care on the regional and…
Since cigarette smoke has effects on the airway epithelium, but also causes endothelial damage and loss of the microvasculature in multiple organs, it seems reasonable to assume that microvascular changes are more present in patients with COPD…
Home DC-ECV in general population patients with an episode of symptomatic recurrent persistent AF, carried out by ECPs, is feasible, safe and is associated with reduced costs.