305 resultaten
We hypothesize that the CPA Talking-with-children-intervention will have a beneficial effect on the mental health and quality of life of maltreated children. We expect that children who participate in the CPA investigation (CPA Talking-with-…
1. Verbeteren van de overleving in vergelijking met de eerdere protocollen van de SKION, in het bijzonder ALL-9 and ALL-10. Doelstelling is om therapie te verminderen voor een deel van de patiënten (TEL/AML1, Down syndroom, geïsoleerd slechte…
Patients with a BMI > 30 kg/m2 in the ICU have a higher incidence of pressure ulcers and wound infections in the ICU compared with patients with a BMI 18-25kg/m2. They develop them sooner during admittance and the severity and time to…
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We postulate that exhaled molecular profiling obtained from ‘breathprints’ by electronic nose: 1. Is associated with the level of asthma control and; 2. Is associated with an inflammatory profile in induced sputum and blood in steroiddependent…
An upfront RBCT aiming at low-normal Hb levels will ameliorate anemia-caused tumor hypoxia-related resistance to chemotherapy before the start of chemotherapy and may decrease secondary anemia-induced endogenous release of cytokines like VEGF,…
Our first hypothesis is that in the two exisiting case management models, the persons with dementia will have less behaviour and mood problems than persons receiving usual care and informal caregivers experience better mental health compared to…
There are predictive markers of treatment response (or non-response) at baseline or during early beginning of treatment?
Part A: In clinical practice the use of simplified quantitative methods and procedures can be fully validated against complex quantitative kinetic measures. Part B: Test-retest repetability of different SUV measures, metabolic and anatomic volume…
It is hypothesized that the use of a biological mesh will improve primary perineal wound healing and prevent secondary perineal hernia formation compared to primary closure of the perineum.
To acquire experience with sputum induction and LPS challenge techniques.
Dietary inorganic nitrate supplementation will decrease O2 cost of exercise in patients with mitochondrial myopathy.
The objective of this study is to determine whether retention of cerclage after PPROM reduces chorioamnionitis, improves latency (without a significant increase in chorioamnionitis), and lessens neonatal morbidity.
The kujala patellofemorla painscore has a good test-retest reliability and also the internal consistency is good.
Our hypothesis is that ID in children with CF is common, and is caused by the combination of an absolute- and a functional-ID, which leads to relative anemia. In this study we will investigate the prevalence and etiology of ID in CF children.…
We will develop a bi-daily low-dose metronomic treatment schedule with paclitaxel in a convenient oral formulation and test whether this therapy has significant anti-angiogenic and anti-tumor activity.
Atrial fibrillation (AF) is the most common cardiac arrhythmia with a prevalence of 1-2% in the general population, increasing with age. It is associated with a 5-fold increased risk of stroke if untreated. While anticoagulant agents are effective…
To determine whether sunitinib rechallenge in patients with mRCC, who had benefit (defined as stable disease for at least 6 months) from prior treatment with sunitinib and who progressed on both sunitinib and second-line therapy (or were without…
Reproducible test-retest assessment of [18F]FDG PET.