189 resultaten
Discontinuation of long term use of antipsychotics for behavioral symptoms in patients with mental retardation does not lead to deterioration in mental functioning.
We hypothesize that rectal NSAID prophylaxis use will have significantly risen in comparison to the 2013 survey. We hypothesize biliary endoscopists will show a significantly better risk factor recognition than general gastroenterologists. We…
Null hypothesis: the 8 centres with different cardiac rehabilitation (CR) programmes do not differ from each other with regards to the effectiveness.
The natural experiment of COVID-19 related governmental measures of home confinement and social distancing has led to a decrease in physical activity levels of school going adolescents of Punjab, India.
We hypothesise that the diet over time has become healthier and more sustainable. Our current study was set up to (1) identify the differences in food consumption and nutritional quality over the course of 20 years in the Netherlands using the…
To test whether implementing a bundle of specific measures during the night shifts at the A&E department improves sleep quality and general physical and psychological well-being Investigate whether this bundle of measures 6 months after…
Based on the human milk composition, Nutricia Research has developed a new infant formula with a new fat blend, more similar to that of human milk. This new formula is currently being studied for safety and its effects on growth. The comparator used…
Repetitive ePIPAC-OX as a palliative monotherapy is a feasible, safe, tolerable, and potentially effective treatment for isolated unresectable colorectal peritioneal metastases, with low and predictable costs and a low systemic uptake of oxaliplatin…
HCQ causes both autophagy inhibition and chromatin modification, thereby (re)sensitizing tumor cells to EGFR TKIs, hypothetically increasing response rates after one week.
We hypothesize that in current dermatological practice, there is a undisclosed burden of psoriatic arthritis in psoriasis patients. We wish to discover the prevalence of known and unknown arthritis in these patients, and find clinical and…
We expect the protein synthesis rate in (avascular) femoral bone proximal to the fracture to be lower when compared to healthy femoral bone.
Blue light glasses can manipulate (i.e., inhibite) body melatonine production to re-adjust the circadian rhythm of shift workers, thereby having the potential to enhance viglance, cognitive function, and positive mood during night shift work.
There is clear medical need in pediatric high-grade MDS and JMML to control disease pre-SCT without the disadvantages associated with intensive chemotherapy. So far no agents have been successfully applied in this window, or are specifically…
With implementation of the AWR we expect a reduction in the total amount of radiographs requested, without missing any clinical relevant fractures. We also expect a reduction in overall waiting times at the ED and a total amount of cost savings…
Please see trial registration NL5809 for more information
To explore the positive, negative or lack of effect that these components have (isolated and combined) on tinnitus disability.
We want to determine the influence and safety of probenecid on sorafenib pharmacokinetics. By inhibiting the OAT6 transporter there might be a faborable effect on Hand-foot syndrome
The present study aims to get more insight into the use of oral anticancer agents in daily practice.