49 resultaten
Screening of esophageal cancer can be improved by the optical detection of field cancerization
The goals of treatment in Crohn’s disease have evolved in recent years from symptom control to healing of mucosal lesions, usually visualized by endoscopy. Potent therapeutic agents, such as anti-TNF agents, have made restoration of mucosal…
Changes in the sleep/wake pattern can be predictive of changes in mood in patients with bipolar disorder.
The primary objective of this study is to review the prevalence of pelvic organ prolapse after laparoscopic hysterectomy compared to vaginal hysterectomy. Because the uterosacral ligaments are the important structure for vault suspension after…
We believe we can extend current insights into the effectiveness of nudging by examining neural correlates in two specific areas important for choice architecture; the role of social influence, and the role of color cues in product evaluation and…
In 1987, MMR vaccination was implemented in the national immunization program of the Netherlands (NIP) by offering vaccinations to children at the age of 14 months and 9 years. Consequently, the annual mumps incidence decreased dramatically, not…
There is growing evidence that gut permeability (or a 'leaky gut') can be linked to metabolic health and might therefore be involved in development of metabolic disorders related to the metabolic syndrome. We hypothesize that gut…
1. To assess the safety and tolerability of different doses of a single IV injection of OTL-038 2. To assess the efficacy of ascending doses of a single IV injection of OTL-038 in detecting ovarian, renal cell or endometrial cancer during surgery by…
Reveal common mechanisms of compulsivity in OCD and GD and disorder specific characteristics of aspects that have been related to compulsivity: confidence in relation with preference for risky and ambiguous behavior, and (negative) outcome…
Exploratory study to develop hypotheses
PD-L1 is up to now the only marker that has been validated for the selection of patients treated for non-small cell lung cancer who might benefit from the treatment with PD-1/PD-L1 inhibitors. Thus far, PD-L1 status is assessed with histology, being…
Early nutrition in preterm infants is essential for growth and neurodevelopment. The last decades more aggressive nutrition has been implemented in clinical practice to ensure optimal growth and thereby optimal neurodevelopmental outcome, as…
The use of PEG-asc could contribute a significant decrease in potassium values a potentially cause serious clinical adverse events.
What is the effect of the systemic antibiotic therapy on the number and diversity of specific bacterial groups in fecal samples of pediatric patients with cancer?
Inflammatory Bowel Disease patients using thiopurines are at higher risk of developing liver abnormalities than IBD patients without thiopurine exposure.
Vitamin D plays an integral role in calcium and phosphorus homeostasis. A low vitamin D status can occur as a result of reduced synthesis due to lack of sun exposure, decreased intake or absorption, increased hepatic catabolism, or decreased…
Implementation of Syncope Algorithms (SAs) in the Netherlands will increase diagnostic yield, avoid unnecessary admissions and improve quality of life (QoL) by offering timely diagnosis & treatment
There is no difference in terms of function between patients who had an olecranon fracture which has been operated with tension band wiring or with plate fixation
Increased knowledge in the physiological recovery after SHiP could contribute to appropriate counseling about the emotional impact of the event and could lead to a more extensive follow-up to recognize the need for psychological help of both women…