16 resultaten
We postulate that exhaled breath sampling by an electronic nose can distinguish and adequately identify smell-prints from: 1. Atopic patients without airway obstruction 2. Non-atopic patients without airway obstruction 3. Atopic patients with…
Patients with moderate to severe COPD, CHF or CRF have been shown to suffer from exercise intolerance, muscle weakness and abnormal changes in body composition, irrespective of the degree of primary organ failure. Therefore, it seems reasonable to…
Currently, no effective, non-toxic medical therapy is available for Cushing's disease. Corticotroph adenomas express both somatostatin receptor subtype 5 and dopamine receptors. SOM230 is a new somatostatin analog which binds to 4 of 5…
There is a relationship between personality factors and prognosis (i.e., mortality; recurrence of disease), also after correction for tumor staging. Both personality and QOL play a role in the relationship between chemotherapy/radiotherapy and…
In lungcancer bone metastases appear frequently en they are an important cause of pain. The expectation is that Bondronat® gives a fast pain reduction. In this phase II study will be examined whether this fast pain reduction indeed occurs and if…
We hypothesize that membrane-residing gangliosides are elevated in obese insulin resistant subjects and correlate to peripheral insulin resistance. Furthermore, we hypothesize that the perturbation of the insulin signaling cascade by elevated…
- The level of psychotic reactivity differs between psychotic trait, state, and illness groups - Psychotic reactivity is mediated by biological reactivity in terms of dopamine and cortisol reactivity - The level of psychotic reactivity is…
To test if an intraoperative NIRF camera system can detect a NIRF optical contrast agent for SLN in patients with palpable breast cancer.
Nocturnal FFA levels are higher in obese insulin resistant subjects and are less sensitive to the FFA lowering effects of a â-receptor blocker.
To investigate the diagnostic value of the mannitol challenge test compared to the eosinophilic inflammation in the airways.
Rheumatoid arthritis patients have an increased risk on developing cardiovasculair disease compared to healthy controls. In this study we explore the influence of disease actitivity on certain cardiovascular parameters (glucose intolerance; lipids;…
We postulate that exhaled breath sampling by an electronic nose can adequately identify newly presented patients with COPD in an at risk population ((ex-)smokers), regardless of symptoms.
Reduction of the severity of functional mitral regurgitation using a percutaneously delivered implanted device.
1. Pre- and post-hydration using a sodium bicarbonate infusion scheme is an effective method to prevent CIN from occurring. 2. The current protocol is efficient in identifying high risk patients. 3. Microalbuminuria and microglobulinuria can…