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We hypothesize there is a difference in CPM between the protocols
The hypothesis is that patients with low anti-TNF drug levels have a higher risk of loss-of-response to anti-TNF drugs compared to patients with high anti-TNF drug levels.
We hypothesize that an evidence based diagnostic algorithm, using fewer and preferably the least invasive diagnostic modalities can approach the accuracy of the complete panel of diagnostic tests.
Breast cancer is the most common type of female cancer worldwide. Early detection has proven to have a positive influence on the prognosis and survival rate. An important aid in the detection and diagnosis of breast cancer is the use of medical…
It is the aim of this study to establish an integrated risk profile including clinical risk factors, AF recurrence patterns, anatomical and electrophysiological characteristics, circulating biomarkers and individual genetic background, to predict…
Nonsimultaneous current steered pulse trains will lead to a single pitch percept whilst reducing the amount of current in comparison to conventional monopolar stimulation
We hypothesize that medical nutrition (PN and EN) compared with no medical nutrition (only oral nutrition) will be associated with better maintenance of nutritional status (fat- and fat free (muscle) mass and body weight), functional capacity,…
There is no relationship between the duration of the procedure under PSA and the incidence of atelectasis and/or respiratory symptoms.
Repetitive ePIPAC-OX as a palliative monotherapy is a feasible, safe, tolerable, and potentially effective treatment for isolated unresectable colorectal peritioneal metastases, with low and predictable costs and a low systemic uptake of oxaliplatin…
Objectives are: 1) To determine the feasibility of an OA educational self-management course, by assessing the appreciation of health care providers and participants, participation and barriers and facilitators to participation. 2) To determine…
We hypothesize that in current dermatological practice, there is a undisclosed burden of psoriatic arthritis in psoriasis patients. We wish to discover the prevalence of known and unknown arthritis in these patients, and find clinical and…
Providing vascular surgical patients and vascular surgeons with decision support tools will improve the level of shared decision-making during consultation, increase disease-specific knowledge and quality of life and decrease decisional conflict.
To explore, whether markers of mitochondrial dysfunction measured in isolated PBMCs or immune cell subpopulations differ between subjects with mitochondrial disorders and cardiomyopathy and healthy volunteers.
To identify (both primary and acquired) resistance mechanisms to chemo-immunotherapy (obtained by less invasive procedures (NGS on ctDNA in blood & urine, exhaled breath or microbioma in stools alone or in combination)) and provide new…
We aim to test the accuracy of Western gastroenterologists in differentiating T1 CRCs from its precursor lesions and subsequently in estimating invasion depth
We hypothesize that by using different imaging techniques, we can give a good characterization of the bone marrow microenvironment in advanced-stage myelofibrosis, before and during treatment with ruxolitinib.
We expect the protein synthesis rate in (avascular) femoral bone proximal to the fracture to be lower when compared to healthy femoral bone.
Postoperative change in deltoid volume following reverse shoulder arthroplasty is related to functional outcome
A safe RP2D of Vyxeos®/CPX-351 in combination with clofarabine can be identified in this phase 1b study.