206 resultaten
We expect brain activity and brain reactivity to change as satiation progresses. ROI are : Brainstem (dorsal vagal complex (DVC), nucleus tractus solitarius (NTS), parabrachial nucleus (PBN)), Hypothalamus, Insula, overlying operculum, secondary:…
Whole Body Vibration (WBV) applied via a chair has positive chronic effects on cognitive function of older people.
The goal of this study is to identify and validate recently discovered and novel biomarkers of pathophysiology, diagnosis, classification, disease activity, prognosis, treatment susceptibility, and treatment efficacy in chronic inflammatory…
The quality of human milk shows an association with the women's diet and lifestyle.
We hypothesize that the commercially available CE-marked over the scope Pro-select Padlock clip is able to clip a gastic/duodenal SET, where after full thickness resection of the SET can be achieved using a normal
To determine the epidemiology, diagnosis and prognosis of enterovirus (EV) and parechovirus (HPeV) infection in Dutch children. Hypotheses: 1. EVs are one of the most important viral agents of infection in Dutch children; 2. EVs are the major cause…
Eating rate may be related to overweight. Due to a high eating rate, there may not be sufficient time to develop appropriate feelings of satiety, leading to overconsumption. We hypothesise that when eating rate is high, the ad libitum food intake is…
Using Irreversible Electroporation on locally advanced pancreatic adenocarcinoma deemed unresectable during explorative laparotomy, will increase progression free survival and median overall survival.
We hypothesize that a conversation aid and information brochure for patients, and a communication training for physicians improves satisfaction and quality of the discussion about potential treatment restrictions at the internal medicine outpatient…
We believe that a routine graft biopsy at 6 and 12 months together with graft function represents the best surrogate marker for late graft loss.
We hypothesize that age-related changes in hepatic and intestinal drug metabolism affect the pharmacokinetics of paracetamol.
We will identify clinical and cancer treatment related risk factors associated with hearing loss, tinnitus and vertigo. We will determine the prevalence of hearing loss, tinnitus and vertigo in a prospective cohort of CNS/ solid tumor patients.
Short-term cognitive behavioral therapy (CBT) given by primary health care workers with patients with chronic benzodiazepine use and new patients in the family practice with sleepinsdisorder, hypothised that CBT results in reduction of…
Maintenance thalidomide delays the time to progression with 50% in patients who do not progress after > 3 cycles of pemetrexed containing chemotherapy.
NAVA (neurally adjusted ventilatory assist) is a newform of artificial respiration, based on the electrical activity of the diafragma. We want to investigate wether there are fysiological differences between the conventional mode and NAVA.
A relationship can be identified between HbA1c levels and self-management and quality of life. It appears better self-management skills result in a larger improvement of HbA1c levels, and the other way around, getting control over HbA1c levels is a…
Type 2 diabetes is cause by progressive beta-cell dysfunction against a background of obesity and insulin resistance in susceptible individuals. Peroxisome proliferator-activated receptor (PPAR) gamma-mediated mechanisms are involved in the…
Develop a screening tool to identify children at risk of posttraumatic stress disorder after an accident.
Het is veilig en haalbaar om in 1-2 gastroscopieen zowel een BDstent te plaatsen als brachytherapie toe te dienen.
Salt restriction is an effective strategy to attenuate or prevent VEGF inhibitor-induced toxicity, primarily the rise in blood pressure.