65 resultaten
Recently, (changes in) the gut microbiome (flora / bacteria) have been associated with obesity and insulin resistance, and other cardiovascular risk factors or atherogenic processes. Venous thrombosis shares these risk factors, probably by a shared…
The aim of this study is to assess long term scar quality of deep dermal burns after debridement with hydrosurgical excision versus conventional tangential excision.
We hypothesize that anxiety symptoms worsen after follow-up imaging compared to patients baseline anxiety levels.
Addition of alternative tests (TEG/ROTEM® and/or TGA) which reflect the whole hemostatic status of a patient might help recognizing the level of thrombin formation and fibrinolysis and improve care in ECMO patients and potentially reduce the risk of…
What is the prevalence of dysplasia or carcinoma in patients with Crohn's disease that undergo surveillance endoscopy with chromoendoscopy-guided confocal laser endomicroscopy?
The manual knee-rotation-test in 90 degree flection is reliable
Chemodenervation by lidocaine of the m. vastus intermedius and the m. rectus femoris improves gait pattern in stroke patients presenting a stiff knee gait.
Sarcoidosis is a granulomatous disorder of unknown cause. Current therapy is immunosuppressive, not curative and often ineffective, as we do not thoroughly understand the underlying pathogenesis. Oral corticosteroids are the first line of therapy in…
1. What are characteristic (neuro)physiological factors of fatigue in disease-free cancer patients? 2. To which degree can these factors be influenced by Cognitive Behavior Therapy?
The overall aim of this study is to implement bariatric surgery including the multidisciplinary care pathway around the procedure for unsuccessfully treated adolescents with severe obesity in the Netherlands. Therefore, feasibility, efficacy and…
In recent years several studies have been published about colorectal interval carcinomas, carcinomas that develop in patients who are under colonoscopic surveillance. One of the reported explanations for interval carcinomas is incomplete removal of…
Using Irreversible Electroporation on locally advanced pancreatic adenocarcinoma deemed unresectable during explorative laparotomy, will increase progression free survival and median overall survival.
We hypothesize that a conversation aid and information brochure for patients, and a communication training for physicians improves satisfaction and quality of the discussion about potential treatment restrictions at the internal medicine outpatient…
We believe that a routine graft biopsy at 6 and 12 months together with graft function represents the best surrogate marker for late graft loss.
Age associated molecullar processess are involved in rotator cuff degeneration and the presence of rotator cuff tears
By developing a model which predicts the risk of bleeding with coumarin use, patients can be treated more effectively, potentially avoiding the need for specific antidotes. Besides decreasing the risk of bleeding (potentially resulting in less…
The implicit training (AAT) added to standard behaviour therapy will reduce relapse rates after treatment when compared to the control group.
The goal of this study is to determine whether radiosensitization with carboplatin or the addition of Isotretinoin to maintenance therapy improves cure rates for children with other than average risk medulloblastoma/PNET.