27 resultaten
We hypothesize that a single night of short sleep duration (4 hours), compared to normal sleep duration (8 hours) reduces metabolic flexibility, increases insulin resistance and thereby reduces HPA-reactivity. Furthermore, we hypothesize that a…
The hypothesis is that the test food with the lower glycemic response exerts a more positive effect on exercise performance than the test food with a higher glycemic response.
Primary hypotheses The primary hypothesis of the present study is that included patients who receive continuous or intermittent oxygen and bilevel positive pressure ventilation during fixed work rate treadmill exercise tests have shorter recovery…
(1) The ‘Ontbijtkoek’ based on teff yields a lower glycemic response (has a lower GI) than the ‘Ontbijtkoek’ based on rye and both ‘Ontbijtkoeken’ will yield a lower glycemic response than the reference test product, white bread; (2) The ‘…
Fatigue affects central nervous system function and, in the setting of the medical profession, could influence specialist performance, patient care and safety. ln contrast to other industries, for example the aviation industry, there are no "…
Visual cues, presented in augmented reality can reduce the severity of freezing of gait evoked during turning in patients with Parkinson’s disease. This reduction is significantly stronger for visual cues than for conventional auditory cues, as well…
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We hypothesize that Iberogast reduces heartburn in patients with functional dyspepsia through an effect on both oesophageal hypersensitivity to acid and on the incidence of reflux episodes.
Currently, the effects of nutrition or specific food components, including those on absorption or metabolism, are mostly studied via parameters in blood samples. To reduce the burden for participants of nutritional intervention studies, there is a…
MRI-ultrasound fusion biopsies of the prostate will detect more clinically relevant tumours (I.e. higher Gleason score) when compared to random ultrasound-guided biopsies in the primary prostate biopsy setting.
We hypothesized that methylphenidate will improve certain aspects of language comprehension and creativity.
Modulation of phosphate intake can affect the antiproteinuric efficacy of RAAS-blockade therapy in CKD patients
We hypothesize that TIPS placement has an significant effect on drug metabolism and bile acid metabolism.
The primary objective of this study is to validate MRI as a functional measuring device for directly monitoring gastric emptying in vivo
Primary Objective: Investigate the effect of modafinil (200 mg) and caffeine (300 mg) on vigilance in low, medium and high caffeine consumers during the circadian trough in order to determine: - To what extend vigilance during the circadian trough…
Intranasal administration of palivizumab is safe in healthy adult volunteers
We expect that patients with a IDH mutation demonstrate an increase in 2-HG on MR spectroscopy. We also expect a positive correlation between in vivo 2-HG on MR spectroscopy and ex vivo concentration in tissue.
The main hyothesis of the experiments is that a dual action antidepressant (duloxetine) modulates functions in specific brain areas involved in the processing bias of emotional stimuli in the context of neutral versus depressed mood.
To determine the role of 5-HT2 and 5-HT1A receptors in learning and memory. It is expected that: 1. An acute dose of MDMA will produce impairments on laboratory measures of learning and memory; 2. MDMA-induced memory impairment will be reversed…