136 resultaten
Since probenecid is a potent multi UGT inhibitor, endoxifen concentrations may be significantly (and clinically relevantly) increased when administered concomitantly with probenecid.
Flexible RPD's have a higher impact on OHRQoL compared to acrylic RPD's.
Primary hypothesis is whether patients with a PTSD the distraction of a positive emotional valence will be more effective in decreasing the vividness and emotionality of a traumatic memory compared to distraction with a neutral task or exposure only…
We hypothesize that especially the reward centres of the brain respond much stronger to processed food in BED, whereas much smaller differences are expected after consuming unprocessed food.
We hypothesize that added neurometabolite measurements can contribute to the interpretation of the ketamine phMRI response.
2C-B generates distinct acute and subacute effects from Psilocybin and placebo
Tumour cell disruption by radiation generates a surplus of neo-antigens that enhances the effect of immunotherapy in solid malignancies as well as malignant lymphomas. The hypothesis is that the combination of immune checkpoint inhibitors and…
We hypothesize that the combination of LEF/HCQ significantly and safely inhibits activity of primary Sjögren’s syndrome and molecular fingerprints will allow prediction of therapy response as well as identification of pathways that confer lack of…
In the first of two substudies, we test the hypothesis that in healthy individuals without ELS, hydrocortisone will be effective in enhancing stress adaptation and extinction learning in an experimental model of exposure therapy, while it is not in…
We hypothesize that consumption of mixtures of 400 grams vegetables and/or fruits for 2 weeks will result in lower ex-vivo induced oxidative DNA damage, increased antioxidant capacity of blood plasma, reduced levels of reactive oxygen species in…
Golimumab 100 mg every 1,5 month has similar trough levels to golimumab 50 mg every month; golimumab 100 mg every 2 months has a similar AUC to golimumab 50 mg every month.
De studie heeft als doelstelling de verschillen in maaglediging en eiwit opname van caseïne met verschillende productmatrix (mineralensamenstelling) te meten.
The higher hardness/protein density of protein gel would delay gastric emptying and protein hydrolysis in humans; MRI technique can used to monitor gastric digestion (in this case: protein hydrolysis) in humans.
Main hypothesis The BENEFIT intervention will significantly increase the number of CVD patients that can maintain the healthy lifestyle behavior most relevant to them for at least one year, compared to care-as-usual. Secondary hypothesis The BENEFIT…
We hypothesize that E171 induces gene expression changes in the colon that explain the inflammatory mechanism of E171 in the colon, which facilitate the development of colorectal cancer. In addition, inflammatory markers will be increased in the…
A 4-month WFPD H0: has no effect on the levels of serum uric acid in patients with gout, hyperuricemia and abdominal obesity in comparison with usual care. H1: results in decreased levels of serum uric acid in patients with gout, hyperuricemia and…
1. DKD patients are salt-sensitive due to a decreased sodium buffering capacity (damaged ESL). As a consequence a high sodium diet will lead to water retention, resulting in increased ECF, body weight and blood pressure. 2. CKD patients are salt-…
We hypothesize that the metabolic effects of acute infusion of acetate are different in insulin resistant subjects compared to lean subjects.
The main objective is to evaluate the efficacy and safety of phenytoin cream in patients with neuropathic pain due to CIAP
A nursing nutrition intervention improves protein and energy intake and performance based on hand grip strength compared to usual care.