325 resultaten
Since probenecid is a potent multi UGT inhibitor, endoxifen concentrations may be significantly (and clinically relevantly) increased when administered concomitantly with probenecid.
Flexible RPD's have a higher impact on OHRQoL compared to acrylic RPD's.
Primary hypothesis is whether patients with a PTSD the distraction of a positive emotional valence will be more effective in decreasing the vividness and emotionality of a traumatic memory compared to distraction with a neutral task or exposure only…
the present study investigates whether Circadian adjusted LED-based (biodynamic) lighting improve cognitive functions, circadian rhytm, behavioral problems (apathy and agitation), Quality of life and mood (depression) in patiënts with moderate- to…
We hypothesise that zoned high compression shorts significantly decrease groin pain in football players without reducing performance.
We hypothesize that especially the reward centres of the brain respond much stronger to processed food in BED, whereas much smaller differences are expected after consuming unprocessed food.
Home blood pressure measurement and 24 hour ambulatory blood pressure monitoring will be in good agreement with each other
1) There will be an effect of anodal stimulation to the left STG with reduced response bias on the signal detection task 2) This effect is specific for speech signal detection.
Cine-MRI is able to detect adhesions in the pouch of Douglas in endometriosis patients by visualizing the presence or absence of the sliding viscera sign.
We hypothesize that added neurometabolite measurements can contribute to the interpretation of the ketamine phMRI response.
2C-B generates distinct acute and subacute effects from Psilocybin and placebo
Tumour cell disruption by radiation generates a surplus of neo-antigens that enhances the effect of immunotherapy in solid malignancies as well as malignant lymphomas. The hypothesis is that the combination of immune checkpoint inhibitors and…
We hypothesize that the combination of LEF/HCQ significantly and safely inhibits activity of primary Sjögren’s syndrome and molecular fingerprints will allow prediction of therapy response as well as identification of pathways that confer lack of…
Our hypothesis is that contratile segment impedance is a marker for EoE-disease activity (histological remission or active disease)
In the first of two substudies, we test the hypothesis that in healthy individuals without ELS, hydrocortisone will be effective in enhancing stress adaptation and extinction learning in an experimental model of exposure therapy, while it is not in…
The study of determinants of cardiovascular disease (CVD) is important because it provides insight in risks and opportunities to reduce the burden of CVD. A major gap in our current knowledge about CVD lies in the way we measure these determinants,…
We hypothesize that consumption of mixtures of 400 grams vegetables and/or fruits for 2 weeks will result in lower ex-vivo induced oxidative DNA damage, increased antioxidant capacity of blood plasma, reduced levels of reactive oxygen species in…
Ongoing activation of the haemostatic system and continuous inflammatory processes contribute to atherosclerotic progression and to the occurrence of atherothrombotic events in PAD.
We hypothesize that TRH effectively antagonize opioid-induced respiratory depression
Golimumab 100 mg every 1,5 month has similar trough levels to golimumab 50 mg every month; golimumab 100 mg every 2 months has a similar AUC to golimumab 50 mg every month.