197 resultaten
Het doel is om de OSDI score te vergelijken van allogene micro serum oogdruppels, toegediend met behulp van het mu-Drop systeem, en het conventionele formaat serum oogdruppels, toegediend met het Meise systeem.
the present study investigates whether Circadian adjusted LED-based (biodynamic) lighting improve cognitive functions, circadian rhytm, behavioral problems (apathy and agitation), Quality of life and mood (depression) in patiënts with moderate- to…
Investigate the acute effect of beetroot juice (BRJ) and high nitrate vegetables (HNV) vs. nitrate depleted beetroot juice (placebo (PL)) on exercise tolerance and vascular function in participants with diagnosed peripheral arterial disease.
Biperiden deteriorate the cognition that biperiden will be used for a challenge model.
The main objective of this study is to determine whether prediabetic individuals and those already diagnosed with type 2 diabetes show differences in sweet taste perception and whether this difference is related to their oral and/or gut microbiota…
Edible insects contain iron at similar concentrations as meat and is mostly organically bound. It is currently not known to what extent iron from edible insects is absorbed in humans.
Ongoing activation of the haemostatic system and continuous inflammatory processes contribute to atherosclerotic progression and to the occurrence of atherothrombotic events in PAD.
The treatment with ciNPT results in a superior healing when compared to the standard treatment (no ciNPT). The rationale behind the secondary outcome is that this treatment leads to improvement of scar quality in comparison to the standard treatment…
Deep brain stimulation (DBS) targeted at the ventral anterior limb of the internal capsule (vALIC) is an effective treatment for treatment-refractory obsessive-compulsive disorder (OCD). However, effective DBS for these patients requires relative…
The objective of this proof-of-concept study is to test the feasibility of the gamma-prototype of the lower limb exoskeleton XoSoft during locomotion-tasks related to daily life in stroke and incomplete spinal cord injury patients in a controlled…
The main objective is to determine the change in CS parameters upon administration of tapentadol in comparison to pregabalin in patients suffering from chronic pain that has a visceral or deep somatic origin.
1. The effect of a single oral dose of L-000830982 versus oral placebo and an intravenous infusion of ethanol versus placebo on tremor over a 8-hour period in men and women with essential tremor will be estimated; 2. The sensitivity and specificity…
This study aims to reject the null-hypothesis that medical treatment and surgical treatment are equally (cost-)effective. This study aims to test the alternative hypothesis that surgical treatment is the most effective regarding pain relief,…
A self help brochure will help people decrease their excessive worrying. and telephonic support will increase the effect.
We hypothesize that UDCA on top of ezetimibe leads to an increased cholesterol excretion via the feces by stimulating ABCG5/8 and preventing absorption of cholesterol due to blocking NPC1L1 and therefore promoting elimination of cholesterol from the…
Inhalation of rhDNase before sleep increases the expiratory flow at 25% of the actual forced vital capacity (MEF25) compared to inhalation of rhDNase in the morning.
We hypothesised that this strategy could lead to a considerable and relevant change of prescribing behaviour in the desired direction.
The study of determinants of cardiovascular disease (CVD) is important because it provides insight in risks and opportunities to reduce the burden of CVD. A major gap in our current knowledge about CVD lies in the way we measure these determinants,…
A new health system is being validated on heart rate variability; galvanic skin response and oxygen saturation.