709 resultaten
The scientific hypothesis of the present study is that supervised implementation of the guideline “Oral health care in (residential) care homes for elderly people” is more effective in improving oral health and oral health care of the residents when…
The aim is to investigate the effects, costs, and feasibility of an evidence-based professional-directed implementation strategy to implement the Dutch peri-operative guidelines, i.e. to achieve a higher adherence to these guidelines. It is…
The objective of this pilot study is to evaluate the feasibility of and the satisfaction with a newly developed online self-management program for spousal caregivers of patients with (very) early-stage dementia including prodromal dementia (MCI due…
It is hypothesize that -performance on a cognitive test battery (CANTAB) will be negatively associated with brain glutamate concentrations in adults with 22q11DS -Cognitive functioning will improve after riluzole administration compared to placebo.
To investigate the acute responses occuring in the esophageal mucosa of EoE patients after local allergen provocation
Primary hypothesis is whether patients with a PTSD the distraction of a positive emotional valence will be more effective in decreasing the vividness and emotionality of a traumatic memory compared to distraction with a neutral task or exposure only…
We aim to assess the effects of tyrosine supplementation on prefrontal brain activation, as measured by a combination of fNIRS and EEG, during response inhibition and working-memory performance in older adults. We will also assess whether…
It is expected that the drink will contribute to an improved postprandial glycaemic response and to an increase of satiety in subjects with type 2 diabetes mellitus.
The primary objective is to determine whether JWH-018 can be safely administered in healthy volunteers in doses up to 3 mg. Therefore participants will be continuously monitored by a medical doctor and vital signs, laboratory clinical safety and…
Wheelchair mobility skills training and wheelchair fitness training will both increase the level of physical activity in wheelchair using children and adolescents. Wheelchair fitness training prior to wheelchair mobility skills training will show a…
Primary hypotheses The primary hypothesis of the present study is that included patients who receive continuous or intermittent oxygen and bilevel positive pressure ventilation during fixed work rate treadmill exercise tests have shorter recovery…
Red pepper might prevent reduction of energy expenditure and elevation of hunger as a result of energy intake restriction.
The hypothesis is that an accurate history, conventional markers of sensitization, IgE antibodies in the serum and positive SPT, and more advanced techniques (MRAs and component resolved diagnosis (CRD)) might predict clinical allergy to cashew nuts…
The Internet 'Self-Examination Therapy' (SET) on anxiety, depression and burn-out wil be effective in reduction of complaints (depression, anxiety, burn-out).
Bezafibrate will significantly reduce post-prandial non-HDL cholesterol in patients with Familial Dysbetalipoproteinemia compared to placebo.
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To prospectively assess the efficacy of combined pan-chromoendoscopy and confocal colonoscopy for the detection of neoplastic lesions in patients at high-risk for CRC. Two issues will be addressed: 1. Does pan-colonic chromoendoscopy improve the…
The objective of the study is to assess the impact of a proactive policy of offering EA at the start of labour before maternal request in women with a child in occiput presentation allowed to try a vaginal delivery, on maternal pain reduction,…
We hypothesize that acetaminophen and nimodipine have a positive influence on postictal phenomena after ECT induced seizures and this is mediated by a reduction of postictal cerebral hypoperfusion.
1. In normoglycaemic critically ill children exogenous glucose administration diminishes endogenous glucose production; 2. Elevated blood glucose levels in critically ill children are caused by the sum of an increased endogenous glucose production…