56 resultaten
The results from this trial will provide evidence on whether structured risk assessments and customized maternity care for high-risk pregnant women by maternity care providers is feasible in terms of effectiveness, especially regarding maternal…
The hypothesis is that the metabolic age, representing a health score will be lower after nine weeks of personalized dietary intervention compared to the control arm (without dietary advice). The phenotypic flexibility or resilience (the ability to…
a. Ascorbic acid in combination with metformin (500mg BD) improve the glucose tolerance with a daily dose of 500mg over a period of 12 months. b. Ascorbic acid with metformin reduce the adverse effects/events. c. Acetylesalicylic acid in…
We hypothesize that the underlying mechanisms of the varying response in multiple parameters within an individual can be attributed to variability in the causal path between drug administration, drug tissue distribution, and tissue receptor…
Hypothesis 1: We expect to find an approach bias in forensic sexual offenders and in sexual addicts. Hypothesis 2: The proposed intervention will cause a decline in approach bias in forenisc sexual offenders and sexual addicts, compared to the…
Treatment with oral iodine prevents deterioration of symptoms in COVID-19 patients admitted to a hospital.
Effect study: A smoking cessation intervention, initiated after cervical cancer screening in Dutch general practice by the practice assistant, has effect on the number of women smokers performing a quit attempt (in comparison to standard care).…
Youth at intermediate vocational education (ROC's) show excessive alcohol and drug use, which can have various detrimental consequences. For this vulnerable group of youngsters a targeted, multicomponent plan of attack was developed in…
The aim of the present study is to investigate whether EMDR is an effective method to treat low self-esteem and if this is more effective than CBT. Hypothesis: 1. Participants will improve on measures of self-esteem, psychological symptoms and…
We hypothesize that consumption of 70 mL of concentrated red beetroot juice will result in a significant increase in urinary NOC levels, and that the same amount of beetroot juice in combination with 1 g vitamin C will result in a decrease in…
•Bicruciate preserved tibia tray for TKA is at least as efficient and safe as the conventional tibia tray for TKA with elimination of the ACL. •TKA with the use of Signature™ alignment guide is at least as efficient and safe as TKA with the use of…
To determine the feasibility of a home based rehabilitation program delivered by means of a tablet-pc for patients after THA To get a first impression of the clinical effectiveness of the rehabilitation program
1) Feasibility of EMDR in older adults (age 60+) is comparable to younger adults (age 20-60); 2) EMDR treatment of PTSD results in improvement of PDs and improvement of cognitive functioning. 3) Somatic and psychiatric comorbidity are negatively…
The tested intervention (level 5 intervention of Triple P, an intensive individual training for the family of children with behavioural problems) will cause a decrease in behavioural problems in children, dysfunctional parenting styles in parents,…
The two tested interventions (Good Behavior Game and parent management training) will cause a decrease in aggression, victimization, disruptive behavior, anxiety and depression in elementary school children.
Cabozantinib improves overall survival in patients with hepatocellular carcinoma compared with placebo
The early stages of cardiovascular disease (CVD) generally cause non-specific or atypical symptoms that patients often do not spontaneously mention to their general practitioner. This makes that new onset CVD is easily missed. A more proactive…
The aim of this study is twofold: 1)To assess the effectiveness of a CPG converted into a CDSS, in actually preventing the development of WSLs during orthodontic treatment with fixed appliances compared to usual preventive measures. 2)To evaluate…
We hypothesize that catheter based selective renal denervation of the native kidneys in renal transplant recipients will improve blood pressure control and diminish the number of antihypertensive drugs.
1.We expect participants in the experimental condition to show a reduced gmbling behaviour 2. We expect participants in the experimental condition to show a decrease in approach bias towards gambling cues, and weaker approach implicit associations…