160 resultaten
rt-PA administration by retinal branch vein way in CRVO patients improves final BCVA.
Subjectieve en objectieve evaluatie van het therapeutische effect van laag-gedoseerde radiotherapie op de pijn en functiebeperking ten gevolge van milde artrose van de heup
Na afloop van deze multicenter RCT zijn we in staat de orthopedisch chirurg te vertellen welke chirurgische behandeling het beste is voor therapieresistente verkalkende tendinitis.
Het onderzoeken van de effectiviteit van het Patiënt en Partner Educatie Programma 4ALL (PPEP4All) voor patiënten met een PAE en/of partner/mantelzorger.
Time to recurrence of sustained VT (longer that 30 seconds or with hemodynamic instability) or VF with or without documented ICD therapy (shock or ATP) for VT of VF will be longer in patients randomized to substrate based ablation than in patients…
The hypothesis is that offering CBT in a group format while discontinuing antidepressant medication will reduce the high relapse rates in remitted anxiety disorder patients who discontinue pharmacological treatment.
90-day treatment with a selected probiotics mixture can reconstitute the microbiome diversity after antibiotic treatment for community-acquired pneumonia.
Patient with incurable disseminated left-sided colonic cancer are better palliated by colonic stenting than surgery measured by hospital free survival in "good health"(WHO-score 0 or 1) Colonic stenting is cost effective in patients with…
Administration of fluoxetine during late brain development (adolescence), but not in adulthood, will result in abnormal outgrowth of the 5-HT system. This long-lasting disturbance of the 5-HT system may be visualized using MRI techniques and can…
To develop a dosing nomogram of irinotecan in patients homozygous polymorphic for UGT1A1*28 and/or UGT1A1*93 in order to reduce the incidence of severe irinotecan-associated toxicity, defined as febrile neutropenia in the first 2 cycles (amendment…
The RAINBOW study: Rheumatoid Arthritis ImplemeNtation of Biological dose Optimization in real World
We hypothesize that a multifaceted implementation strategy can stimulate the use of tight control and bDMARD dose optimization in clinical practice, measured by decreased bDMARD use and non-inferiority on disease activity at 18 months.
1. It is hypothesized that participation in the Active plus program contributes to an increase in physical activity behaviour among older adults; 2. Additionally receiving physical and social environmental information results in an extra increase…
Although current treatment programs for adolescents with substance use disorders show beneficial outcomes, post-treatment relapse rates remain high and leave room for further improvement. Patients with an addiction show neurocognitive deficits and…
Concomitant physical symptoms frequently complicate the treatment of common mental disorders. The objective of this study is to investigate effects and costs of a Transmural Collaborative stepped Care model with Consultation Letter (TCCCL) to the…
Primary objective: - To evaluate the safety and tolerability of NT-0167 in healthy volunteers Secondary: - To evaluate the pharmacokinetic (PK) profile of NT-0167 in healthy volunteers after the administration of single ascending (SAD) and multiple…
Chronic allograft nephropathy is the main cause of long-term renal transplant failure. The pathogenesis involves amongst others calcineurin inhibitors. We performed a multicenter randomized trial to study the effects of withdrawal of ciclosporin (…
Minimally invasive pancreatoduodenectomy is as safe as open pancreatoduodenectomy
Caregiver mediated exercises next to usual therapy will improve functional outcome for adults with stroke in gait, gait related abilities and ADL with a reduced length of stay (LOS) when compared to usual care alone. In addition we hypothesize that…
Informal caregivers in the experimental group are expected to be more satisfied with the care provided to them and the patient they take care of, to experience a less heavy burden, and to have a better health compared to the informal caregivers who…
Primary objective: To assess the efficacy of thromboprophylaxis with high prophylactic dose LMWH as compared with standard care without systemic thromboprophylaxis in children treated for primary ALL. Secondary objectives: 1. To assess the safety…