838 resultaten
We hypothesize that treating patients with intestinal permeability improving probiotics (in addition to usual treatment; antipsychotic / mood stabilizing treatment) will cause a decrease in psychiatric symptoms (measured with the Brief Psychiatric…
We hypothesize that transient inflammation/infection-associated deep venous thrombosis has a similar recurrence risk as 'classic' provoked deep venous thrombosis.
Allogeneic stem cell transplantation (allo-SCT) is still the treatment of choice for many patients suffering from hematological malignancies, which can only occasionally be cured with conventional chemotherapy. Allo-SCT still associates with a high…
We hypothesize that standardized training for endoscopist comprising endoscopic diagnosis followed by a therapeutic plan and high-quality endoscopic resection performance will reduce the number of recurrence after resection of large non-pedunculated…
By using weekly the clinical rule reporter as the medication review system, the number of hospital readmissions in older patients (> 60 years) will be reduced with 5% (from 20% to 15%). For the Netherlands this may translate into prevention…
Kidney transplantation is the only treatment offering long-term benefit to patients with chronic kidney failure. Urological complications after kidney transplantation, such as urinary leakage and ureteral strictures, are associated with significant…
Patient education on extended anticoagulation pros and cons: a journey app in venous thromboembolism
Our hypothesis is that patients whom receive targeted information about VTE and (extended) anticoagulation treatment with the 'patient journey app' on a daily basis in the week preceding their hospital visit will be more satisfied with the…
What is the influence of protective gear on the performance of basic life support (BLS) by KNRM lifeboat crewmembers during a manikin simulation training
Knee OA is characterized by the presence of crepitus (knee sounds). Therefore, this device is able to record these sounds, while the subject is doing a knee movement, and screen for the presence or absence of osteoarthritis.
The hypothesis states that the time tom complete an emergency airway with Cricath device is significant faster than with Quicktrach device, which will be studied on porcine cadaver models. In the second outcome, the hypothesis states that there is…
It is hypothesize that a non-degradable urethral bulking agent (UBA) is non-inferior in efficacy and superior in cost-effectiveness as compared to mid-urethral sling (MUS) surgery in the treatment of moderate to severe stress urinary incontinence…
The hypothesis is that the 'Shine!' intervention will result in parents having better parenting skills and a higher self-efficacy to twice daily brush their children’s teeth, resulting in better oral hygiene and less dental caries…
Pre-hospital triage in patients with low risk of NSTE-ACS will reveal a large saving in health care resources in favor of the pre-hospital rule strategy with additional GP management. At 12 months the strategy will corroborate with a very low event…
Saphenus blok reduceerd opname duur na epifysiodese van de knie - een triple blind superiority trial
We hypothesize that a single shot saphenous nerve block in combination with general anesthesia would be superior to general anesthesia alone regarding opiod consumption. pain scores. recovery and length of stay in adolecent patients undergoing…
In the proposed study we will investigate the effect
The objective is to investigate whether application of a stepwise work-up strategy in primary care patients with uncontrolled hypertension results in better blood pressure control in a cost-effective manner.
We hypothesize that intramuscular gluteal corticosteroid injection is non-inferior to intra-articular corticosteroid injection in reducing knee pain in patients with knee osteoarthritis.
The effectiveness of the E-health self-management treatment on different domains will be examined. Primarily, it is hypothesized that the treatment results in a lower level of psychological distress, and thereby might facilitate life style changes…
The acceptance and commitment therapy will lead to a greater reduction of depressive and anxiety symptoms in compared to a psycho-education intervention. The acceptance and commitment therapy will lead to less the additional costs and additional…
Treatment with tofacitinib or infliximab show similar changes in lipid and lipoprotein levels in patients with ulcerative colitis