995 resultaten
Recurrent miscarriages is defined as three or more consecutive miscarriages prior to the 20th week of gestation. Whenever the diagnosis ‘recurrent miscarriages’ is established, an underlying cause may be identified in about 25-50% of cases. A…
Prelingually deafened cochlear implant users mostly do not achieve a high level of speech understanding with their cochlear implant (CI). We hypothesize that the information these patients are getting from their CI is often too complex for them to…
The purpose of this study is: 1. To identify clinical and biological predictors for the development of IRIS in HIV infected patients and; 2. To obtain insight into the pathogenesis of this syndrome; 3. To describe the epidemiological pattern of IRIS…
We hypothesize that more participants in the experimental condition, who are offered the computer-tailored feedback program, will quit smoking and that these participants will become more physically active compared to the participants in the control…
We hypothesize that the vascularity of the fibroid is associated with: 1. Growth potential of the fibroid; 2. The fibroid size reduction after GnRHa treatment.
Exploring QOL, hope, treatment motivition, coping en locus of control of patients considering early clinical cancer trial participation.
The incidence and types of infection are comparable in sterile suturing or clean suturing of traumatic wounds. Clean suturing is cheaper, less time consuming and requires less assistence that sterile suturing
The primary objective of the CCR study is to monitor clinically relevant parameters of ACS patients undergoing PCI with a follow-up of 1 year, after updating treatment guidelines of the participating network to include prasugrel as the first line…
Amendment (5-apr-2013): Dosing-time of sunitinib may alter the pharmacokinetics
TEE has proven to be an invaluable tool in evaluation and guiding treatment in both adult and paediatric patients in the operating room and in the ICU. In the ICU the development of smaller TEE probes has led to the trans-nasal introduction of these…
The purpose of this study is to assess the suitability of a high efficient cardiac rehabilitation program from Canada in a Dutch setting in patients with a MI, PCI or CAGB within 3 months prior to inclusion and compare the efficiency of this program…
1. Cancer survivors experience more meaning in life after the intervention; 2. Psychological wellbeing in cancer survivors improves after the intervention.
High-dose, weekly erlotinib is a therapeutic option for EGFR-mutated NSCLC patients with leptomeningeal metastases while on EGFR-TKI therapy. In one of the patients treated with this dose schedule not only the leptomeningeal metastases showed…
Yellow fever specific T cells are present in 70% of patients using immunosuppressive medication versus 99% of healthy volunteers.
8 weeks after the PRF treatment we expect that the electric quantitative sensory testing (eQST) values are higher compared to the eQST values before the PRF treatment. This means that patients can tolerate a higher stimulation threshold. The…
It is expected that using the DEM-DISC will decrease the number of unmet needs and increase the number of met needs in people with dementia and their informal caregivers. Informal caregivers using DEM-DISC are expected to feel less burdened and will…
The aim of this study is to test, by means of a randomized controlled trial, the hypothesis that application of PAS therapy with low-frequency acoustic vibrations to demented patients in nursing homes will lead to a significant decrease of nocturnal…
The combination of breast surgery, radiotherapy and chemotherapy have a profound effect on the deep myofascial level and in turn, they create a vicious circle of adhesions and lack of mobility and pain in muscles, fasciae and joints around the…
Pain Rehabilitation Programs (PRP’s) are proven effective for patients with chronic musculoskeletal pain (CMP). Evidence about the relationship of dose on the effect of PRP however, is unavailable. We hypothesized that shortening PRP will not be…
Background: Injury rate and injury severity of elderly cyclists due to self-induced cycle accidents increase with age. Starting at the age of 55 years, injury risk increases with a factor 4 at the age of 75 years. Injury mechanisms such as slippery…