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The aim of this study is to determine the (cost)effectiveness of a home-based functional training programme as compared to regular physical therapy with regard to the ability to live independently and participation of frail elderly of 75 years and…
Assessment of feasibility of neoadjuvant chemotherapy consisting of docetaxel, cisplatin and capecitabine in resectable localized gastric cancer (stage Ib-IVa) and the introduction of the D1extra-lymphadenectomy as the standardized surgical…
The main objective of the present study is to evaluate (cost)effectiveness of Dementia Care Mapping (DCM)intervention in nursing home dementia care by performing a large RCT study.
We hypothesize that the Ketogenic diet will be cost-effective compared to usual care.
The first aim of this study is to evaluate the development of motor skills (goal directed arm movements) in children with a visual impairment compared to normally sighted peers. Our hypothesis is that children with a visual impairment have poorer…
To determine the correlation between enhancement curves at DCE-MRI with T1-map and the level of histopathological activity.
1. The point of the skin with best possible transcutaneous nerve stimulation correlates with the point of the skin most superficial to the nerves stimulated within a range of 3 mm; 2. Ultrasound will reveal a significant number of sensitive…
Is there a difference in the recurrence rate if you treat a cyst or abscess of the bartholin gland with a marsupialization or placement of a word catheter.
We hypothesize that subjects suffering from hypothalamic dysfunction may have a hyposerotonergic neurotransmission. Therefore we will investigate if there are differences in specific hypothalamic-to-nonspecific [123I]FP-CIT binding ratios using…
The objective of the study is to identify factors associated with anterior knee pain after primary total knee replacement.
The aim of this study is to investigate whether the optical tissue stylet technology can discriminate tissues that are relevant for interventional pain procedures.
We hypothesize that a treatment algorithm that is based on a simple validated measure of health status (CCQ) improves quality of life (as measured on a separate scale) and other classical COPD outcome measurement parameters such as exacerbation…
The primary research hypotheses are: 1. Patients who follow the Onco-Move program will achieve better physical fitness levels, as assessed by objective performance tests, and will report less fatigue than patients in the usual care control group; 2…
Public health authorities have recognized lack of hand hygiene (HH) as one of the important causes of preventable mortality and morbidity at population level. Both at national (UK, USA, Dutch VMS) and international levels (WHO) poor HH has been…
The purpose of this study is to demonstrate the added value of using 'LMA-S in the ambulance with CPR in the Netherlands indigent patients. The hypothesis is that the value of using the LMA-S is located in the safety and speed of placing the…
There is clear medical need in pediatric high-grade MDS and JMML to control disease pre-SCT without the disadvantages associated with intensive chemotherapy. So far no agents have been successfully applied in this window, or are specifically…
Assess of the effect of HD colonoscopy alone or when combined with different I-scan functions compared to standard colonoscopy with respect to adenoma detection rate.
Patients undergoing a minimally invasive oesophagectomy have fewer morbidity, a shorter duration of the intensive care unit (ICU) admission and a better quality of life than following the traditional approach.
To study's primary objective is to establish the effectiveness of a low-threshold guided self-help intervention targeted at improving one's self image in people with anxiety and/or depressive symptoms and low self esteem. We expect to find…
Otosclerosis is an isolated ear disorder which can cause hearing and balance impairment. The cause of these symptoms is a disturbed bone metabolism confined to the area of the otic pit, the embryologic predecessor of the inner ear. Most patients…