19 resultaten
The COL3A1 polymorphism is a inheritable genetic defect, responsible for the increased susceptibility to pelvic organ prolapse in women.
1. Prosthetic valve characteristics (type; location; size resulting in the presence/absence of PPM) are related to functional outcome and quality of life; 2. The incidence/spectrum of prosthetic valve-related complications in adults with CHD differs…
We hypothesize that exercise training improves maximal exercise capacity in adult patients with a systemic RV. Moreover, we hypothesize that exercise training decreases serum NT-proBNP levels and increases quality of life in adult patients with a…
In patient with clinically suspected appendicitis, imaging is needed to substantiate the clinical diagnosis. Imaging accuracy of US and CT is suboptimal, and the associated use of ionizing radiation and iodinated contrast medium are major drawbacks…
Primary objective: To test whether mucosal oxygen saturation has added value to endoscopy and histological examination. Secondary objectives: 1. To test whether detection of hypoxia dependent molecular changes in the mucosa can be used to improve…
Does lipid accumulation in skeletal muscle and the heart effect mitochondrial function in relation to insulin resistance?
We will study which factors differ between the responders to oxygen therapy and the non-responders. Factors that will be studied are for instance patient characteristics, headache characterisics, comorbidities and intoxications.
Our primary hypothesis states that cognitive behavioral therapy will improve quality of life and amend illness cognitions and attitudes in IBD patients. Our secondary hypothesis states that improvements in quality of life are mediated by changes in…
N/A
Pyridostigmine will activate the parasympathetic cholinergic anti-inflammatory pathway and therefore reduce inflammatory signs and symptoms in patients with complex regional pain syndrome.
By using a proactive approach (prompts) compared to a reactive approach CT (computer tailored) program use will be increased by 20 %.
Early prostate cancer may safely be managed with an active surveillance strategy, avoiding overtreatment and the risk of resulting side effects.
No significant difference in results of functional treatment with physical therapy including a form of external support (tape or brace) in comparison with a purely functional treatment strategy with only a physical therapy programme, without any…
By detection of disease specific deviations in emotion processing in unipolar vs bipolar patients, affective neuropsychological tests and fMRI could be used to discriminate between both affective disorders.
We hypothise that women with a history of preeclampsia have accelerated vascular aging in comparison with control women with uncomplicated pregnancies.
We expect a decrease in the expected satiating capacity of the test food after repeated exposure to the low-energy-dense version of the soup and an increase in expected satiation after the repeated consumption of the high-energy-dense soup.
Recent clinical data showed that remote ischemic preconditioning attenuates myocardial damage during cardiac surgery. Classic preconditioning is abolished in diabetic patients. We will investigate the molecular effects of remote ischemic…
1. To investigate the implementation of Schema Therapy (ST) in regular mental healthcare and investigate whether its effectiveness and cost-effectiveness is comparable to the original RCT (Outpatient Psychotherapy for Borderline Personality Disorder…
Whether antibiotic guidance by procalcitonin measurements are able to reduce antibiotic usage and duration in Dutch intensive care units.