2408 resultaten
A 10% point difference between the intervention group and control group in IDM is expected. The sample size calculation is based on a worst-case scenario with regard to precision. For a binomial distribution, the widest distribution and thus largest…
The hypothesis is that patients with low anti-TNF drug levels have a higher risk of loss-of-response to anti-TNF drugs compared to patients with high anti-TNF drug levels.
We hypothesize that an evidence based diagnostic algorithm, using fewer and preferably the least invasive diagnostic modalities can approach the accuracy of the complete panel of diagnostic tests.
Nonsimultaneous current steered pulse trains will lead to a single pitch percept whilst reducing the amount of current in comparison to conventional monopolar stimulation
We hypothesize that medical nutrition (PN and EN) compared with no medical nutrition (only oral nutrition) will be associated with better maintenance of nutritional status (fat- and fat free (muscle) mass and body weight), functional capacity,…
In the first of two substudies, we test the hypothesis that in healthy individuals without ELS, hydrocortisone will be effective in enhancing stress adaptation and extinction learning in an experimental model of exposure therapy, while it is not in…
The natural experiment of COVID-19 related governmental measures of home confinement and social distancing has led to a decrease in physical activity levels of school going adolescents of Punjab, India.
To test whether implementing a bundle of specific measures during the night shifts at the A&E department improves sleep quality and general physical and psychological well-being Investigate whether this bundle of measures 6 months after…
There is no relationship between the duration of the procedure under PSA and the incidence of atelectasis and/or respiratory symptoms.
We expect the protein synthesis rate in (avascular) femoral bone proximal to the fracture to be lower when compared to healthy femoral bone.
Low-load blood flow restriction therapy has beneficial effects on postoperative quadriceps and hamstrings atrophy/strength, at 8 and 14 weeks after bone-patellar tendon-bone anterior cruciate ligament reconstruction, compared to standard care…
We hypothesize that MTX can be quantified in semen and that it is associated with measures of semen quality and DNA fragmentation
Individuals at the top 20% of genetic risk distribution for glaucoma are at a higher relative risk for having glaucoma.
The overall aim of this RCT is to examine whether an individual music intervention can improve the challenging behavior, quality of life, emotional wellbeing and EF of adults with a mild to moderate ID.
We hypothesize that repeated spot urine sampling is non-inferior to a single 24-hour urine collection to estimate 24-hour dietary sodium and potassium intake.
-The combination of center-based CR and a home-based exercise training program will lead to a greater increase in physical activity levels compared to standard care. -Continuation of home-based exercise during a three-month follow-up will lead to…
Young people with a psychotic disorder have the same social goals as their healthy peers, but their social networks are smaller, they participate less often in leisure activities and are less successful in work and education. This impairment in…
We aim to evaluate the efficacy of the `OncoSTRIP', a standardized polypharmacy assessment method, in a group of elderly patients with cancer on medication use satisfaction by using the 'Treatment Satisfaction Questionnaire for Medication…
The precise mechanisms driving onset and course are insufficiently understood, disease progression from a current patient state and/or the development of comorbidities are unpredictable, and the optimal type and time-point for intervention is as yet…