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Post-donation iron supplementation will be an effective strategy to enhance the iron status recovery in whole blood donors with low ferritin levels.
Due to its ability to avoid preterm birth, the neurodevelopmental sequelae of preterm birth could also be prevented by progesterone. However, progesterone may also exert direct effects on the fetus’ developing brain.
Oral bisphosphonate supplementation or the MMR vaccine can be used as immune potentiators when simultaneously administered with BCG, to further amplify the BCG-induced trained immunity response and maximize potential protective effects against COVID…
We hypothesize (hypothalamic) obesity can be treated with GLP-1 analogues in patients with craniopharyngioma.
BCG vaccination may induce (partial) protection against susceptibility to and/or severity of SARS-CoV-2 infection. This will lead to reduced workplace absenteism under health care workers taking care of patients with COVID-19
We speculate that the virome composition of the lean donor and the subsequent interaction between phages and bacteria in the recipients are crucial determinants of stability and diversity of gut bacterial composition and glucose metabolism in humans…
In T2DM patients with DKD, an acute oral sodium load results in less renal sodium excretion than in healthy individuals and non-DKD T2DM, which can be restored by administration of a GLP-1 receptor agonist.
More physical activity will increase protein synthesis rates of muscle tissue and will decrease protein synthesis rates of prostate tissue and prostate tumor tissue.
The main objective of the study is to investigate if positional therapy during sleeping, using the LEFT device, reduces nighttime gastroesophageal reflux symptoms.
Primary Objective To evaluate the safety and tolerability of topical XZ.700 in patients with mild to moderate atopic dermatitis Secondary Objectives To investigate the PD effects of XZ.700 in patients with mild to moderate atopic dermatitis To…
We hypothesize that the combination of LEF/HCQ significantly and safely inhibits activity of primary Sjögren’s syndrome and molecular fingerprints will allow prediction of therapy response as well as identification of pathways that confer lack of…
We hypothesize that BCG vaccination may reduce hospital admission and improve the clinical course of symptoms of elderly people during the SARS-CoV-2 outbreak.
2gr of Cefazolin is effective as prophylaxis for surgical site infections following implant removal below the level of the knee.
The objective of the study is to evaluate safety, tolerability, and pharmacokinetics (PK) of ALKS 6610 after single ascending oral doses in healthy adult subjects.
We hypothesize that probiotics with vitamin K2 producing properties can improve vitamin K status, which will eventually reduce the risk of coronary calcification.
We expect that metformin in combination with lifestyle interventions reduces Antipsychotic induced Weight Gain compared to placebo in combination with lifestyle interventions.
We hypothesize that GABA could improve glucose tolerance and cardiovascular health after long-term supplementation
Foods consisting of whole dairy, butter, beef and locally grown seasonal vegetables with a balanced composition of omega 3 and 6 fatty acids and a wide range of essential micronutrients and anti-inflammatory capacities have a protective effect on…
OTL78 is safe for use in healthy male individuals and patients with prostate cancer. OTL78 binds to malignant prostate tissue and malignant lymph nodes.
The study hypothesis is that the LSD group shows an increase in positive mood and subjective effects between baseline and follow-up after 4 weeks of repeated dosing with LSD compared to the placebo group. An additional study parameter is the…